The Mode of Action of 2-(Thiazol-2-ylthio)-1β-methylcarbapenems against Pseudomonas aeruginosa: The Impact of Outer Membrane Permeability and the Contribution of MexAB-OprM Efflux System-Reference-Cited by-同舟云学术

The Mode of Action of 2-(Thiazol-2-ylthio)-1β-methylcarbapenems against Pseudomonas aeruginosa: The Impact of Outer Membrane Permeability and the Contribution of MexAB-OprM Efflux System

Published:2007-02 Issue:2 Volume:60 Page:129-135
ISSN:0021-8820
Container-title:The Journal of Antibiotics
language:en
Short-container-title:J Antibiot

Author:

Eguchi Ken,Ueda Yutaka,Kanazawa Katsunori,Sunagawa Makoto,Gotoh Naomasa

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmacology

Link

http://www.nature.com/articles/ja200712.pdf

Reference18 articles.

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2. Jones RN . Resistance patterns among nosocomial pathogens: trends over the past few years. Chest 119: 397S–404S ( 2001)

3. Ueda Y, Kanazawa K, Eguchi K, Takemoto K, Eriguchi Y, Sunagawa M . In vitro and in vivo antibacterial activities of SM-216601, a new broad-spectrum parenteral carbapenem. Antimicrob Agents Chemother 49: 4185–4196 ( 2005)

4. Ueda Y, Itoh M, Sasaki A, Sunagawa M . SM-216601, a novel parenteral 1β-methylcarbapenem: structure-activity relationships of antibacterial activity and neurotoxicity in mice. J Antibiot 58: 118–140 ( 2005)

5. Sumita Y, Yamaga H, Sunagawa M . The effect of 1β-methyl substituent and the basicity in C-2 side chain in carbapenem antibiotics on the activity against Pseudomonas aeruginosa oprD2 and nalB mutants. J Antibiot 48: 89–91 ( 1995)

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