The multikinase inhibitor midostaurin (PKC412A) lacks activity in metastatic melanoma: a phase IIA clinical and biologic study

Author:

Millward M J,House C,Bowtell D,Webster L,Olver I N,Gore M,Copeman M,Lynch K,Yap A,Wang Y,Cohen P S,Zalcberg J

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Reference16 articles.

1. Brown CK, Kirkwood JM (2003) Medical management of melanoma. Surg Clin N Am 83: 283–322

2. Budworth J, Gescher A (1995) Differential inhibition of cytosolic and membrane-derived protein kinase C activity by staurosporine and other kinase inhibitors. FEBS Lett 362 (2): 139–142

3. Fabbro D, Ruetz S, Bodis S, Pruschy M, Csermak K, Man A, Campochiaro P, Wood J, O’Reilly T, Meyer T (2000) PKC412 – a protein kinase inhibitor with a broad therapeutic potential. Anticancer Drug Res 15: 17–28

4. Fumoleau P, Gore M, Roelevink M, de Vries M, Smyth J, Aamdal S, Vermoken J, Ravaud A (2000) Phase II trial with antisense oligonucleotide ISIS3521/CGP64128A in melanoma patients: a report from the EORTC/ECSG. Ann Oncol 11 (Suppl 4): 128 (abstr)

5. Ikegami Y, Yano S, Nakao K (1996) Antitumor effect of CGP41251, a new selective protein kinase C inihibitor, on human non-small cell lung cancer cells. Jpn J Pharmacol 70 (1): 65–72

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