Human prostate cell lines from normal and tumourigenic epithelia differ in the pattern and control of choline lipid headgroups released into the medium on stimulation of protein kinase C

Author:

Rumsby M,Schmitt J,Sharrard M,Rodrigues G,Stower M,Maitland N

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Reference96 articles.

1. Ackerstaff E, Pflug BR, Nelson JB, Bhujwalla ZM (2001) Detection of increased choline compounds with proton nuclear magnetic resonance spectroscopy subsequent to malignant transformation of human prostatic epithelial cells. Cancer Res 61: 3599–3603

2. Alessi D (1997) The protein kinase C inhibitors Ro318220 and GF 109203X are equally potent inhibitors of MAPKAP kinase-1β (Rsk-2) and p70S6 kinase. FEBS Lett 402: 121–123

3. Ali AS, Ali S, El-Rayes BF, Philip PA, Sarkar FH (2009) Exploitation of protein kinase C: useful target for cancer therapy. Cancer Treat Rev 35: 1–8

4. Baba S, Engles J, Wahl R (2007) Choline uptake and RNA expression profile in cancerous and normal prostate cell lines: No significant role of choline transporter in PET tracer uptake. J Nucl Med 48 (Supp 2): 335P

5. Beloueche-Babari M, Peak JC, Jackson LE, Tiet M-Y, Leach MO, Eccles SA (2009) Changes in choline metabolism as potential biomarkers of phospholipase Cγ1 inhibition in human prostate cancer cells. Mol Cancer Ther 8: 1305–1311

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