Clinical anticancer drug development: targeting the cyclin-dependent kinases

Author:

Benson C,Kaye S,Workman P,Garrett M,Walton M,de Bono J

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Reference55 articles.

1. Aamdal S, Smyth J, Awada A, Dittrich C, Caponigro F, Djurasinovic N, Marchal B, Yule M (2002) Phase II study of E7070 in patients with metastatic melanoma (stage IV). Eur J Cancer 38: S50

2. Akiyama T, Yoshida T, Tsujita T, Shimizu M, Mizukami T, Okabe M, Akinaga S (1997) G1 phase accumulation induced by UCN-01 is associated with dephosphorylation of Rb and CDK2 proteins as well as induction of CDK inhibitor p21/Cip1/WAF1/Sdi1 in p53-mutated human epidermoid carcinoma A431 cells. Cancer Res 57: 1495–1501

3. Arguello F, Alexander M, Sterry JA, Tudor G, Smith EM, Kalavar NT, Greene Jr JF, Koss W, Morgan CD, Stinson SF, Siford TJ, Alvord WG, Klabansky RL, Sausville EA (1998) Flavopiridol induces apoptosis of normal lymphoid cells, causes immunosuppression, and has potent antitumor activity in vivo against human leukemia and lymphoma xenografts. Blood 91: 2482–2490

4. Bennett P, Mani S, O'Reilly S, Wright J, Schilsky RL, Vokes EE, Grochow L (1999) Phase II trial of flavopiridol in metastatic colorectal cancer: preliminary results. Proc Am Soc Clin Oncol 18: 277

5. Benson C, White J, Twelves C, O'Donnell A, Cruickshank C, Tan S, Gianella-Borradori A, Judson I (2003) A phase I trial of the oral cyclin dependent kinase inhibitor CYC202 in patients with advanced malignancy. Proc Am Soc Clin Oncol 22: 209

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