Dose escalation and pharmacokinetic study of a humanized anti-HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Oncology
Link
http://www.nature.com/articles/6690343.pdf
Reference24 articles.
1. Baselga, J, Tripathy, D, Mendelsohn, J, Baughman, S, Benz, CC, Danits, L, Sklarin, NT, Seidman, AD, Hudis, CA, Moore, J, Rosen, PP, Twaddell, T, Henderson, IC & Norton, L (1996). Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer. J Clin Oncol 14: 737–744.
2. Carter, P, Presta, L, Gorman, CM, Ridgway, JBB, Henner, D, Wong, WLT, Rowland, AM, Kotts, C, Carver, ME & Shepard, HM (1992). Humanization of an anti-p185HER2 antibody for human cancer therapy. Proc Natl Acad Sci USA 89: 4285–4289.
3. Coussens, L, Yang-Feng, TL, Liao, Y-C, Chen, E, Gray, A, McGrath, J, Seeburg, PH, Liebermann, TW, Schlessinger, J, Franke, U, Levison, A & Ullrich, A (1985). Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene. Science 230: 1132–1139.
4. De Potter, CR, Van Daele, S, Van De Vijver, MJ, Pauwels, C, Maertens, G, De Boever, J, Vandekerckhove, D & Roels, H (1989). The expression of the neu oncogene product in breast lesions and in normal fetal and adult human tissues. Histopathology 15: 315–326.
5. Drebin, JA, Link, VC, Stern, DF, Weinberg, RA & Green, MI (1985). Down modulation of an oncogene protein product and reversion of the transformed phenotype by monoclonal antibodies. Cell 41: 695–706.
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