Stable interference of EWS–FLI1 in an Ewing sarcoma cell line impairs IGF-1/IGF-1R signalling and reveals TOPK as a new target-Reference-Cited by-同舟云学术

Stable interference of EWS–FLI1 in an Ewing sarcoma cell line impairs IGF-1/IGF-1R signalling and reveals TOPK as a new target

Published:2009-06-02 Issue:1 Volume:101 Page:80-90
ISSN:0007-0920
Container-title:British Journal of Cancer
language:en
Short-container-title:Br J Cancer

Author:

Herrero-Martín D,Osuna D,Ordóñez J L,Sevillano V,Martins A S,Mackintosh C,Campos M,Madoz-Gúrpide J,Otero-Motta A P,Caballero G,Amaral A T,Wai D H,Braun Y,Eisenacher M,Schaefer K-L,Poremba C,de Alava E

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Link

http://www.nature.com/articles/6605104.pdf

Reference43 articles.

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2. Abe Y, Takeuchi T, Kagawa-Miki L, Ueda N, Shigemoto K, Yasukawa M, Kito K (2007) A mitotic kinase TOPK enhances Cdk1/cyclin B1-dependent phosphorylation of PRC1 and promotes cytokinesis. J Mol Biol 370: 231–245

3. Amsellem V, Kryszke MH, Hervy M, Subra F, Athman R, Leh H, Brachet-Ducos C, Auclair C (2005) The actin cytoskeleton-associated protein zyxin acts as a tumour suppressor in Ewing tumour cells. Exp Cell Res 304: 443–456

4. Ayllon V, O'Connor R (2007) PBK/TOPK promotes tumour cell proliferation through p38 MAPK activity and regulation of the DNA damage response. Oncogene 26: 3451–3461

5. Benini S, Perbal B, Zambelli D, Colombo MP, Manara MC, Serra M, Parenza M, Martinez V, Picci P, Scotlandi K (2005) In Ewing's sarcoma CCN3(NOV) inhibits proliferation while promoting migration and invasion of the same cell type. Oncogene 24: 4349–4361

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