Immunosuppressive effects of radiation on human dendritic cells: reduced IL-12 production on activation and impairment of naïve T-cell priming

Author:

Merrick A,Errington F,Milward K,O'Donnell D,Harrington K,Bateman A,Pandha H,Vile R,Morrison E,Selby P,Melcher A

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Reference40 articles.

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2. Banchereau J, Steinman RM (1998) Dendritic cells and the control of immunity. Nature 392: 245–252

3. Cao MD, Chen ZD, Xing Y (2004) Gamma irradiation of human dendritic cells influences proliferation and cytokine profile of T cells in autologous mixed lymphocyte reaction. Cell Biol Int 28: 223–228

4. Celluzzi CM, Falo LD (1998) Physical interaction between dendritic cells and tumour cells results in an immunogen that induces protective and therapeutic tumour rejection. J Immunol 160: 3081–3085

5. Chakravarty PK, Alfieri A, Thomas EK, Beri V, Tanaka KE, Vikram B, Guha C (1999) Flt3-ligand administration after radiation therapy prolongs survival in a murine model of metastatic lung cancer. Cancer Res 59: 6028–6032

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