Hypoxia enhances the expression of autocrine motility factor and the motility of human pancreatic cancer cells

Author:

Niizeki H,Kobayashi M,Horiuchi I,Akakura N,Chen J,Wang J,Hamada J-i,Seth P,Katoh H,Watanabe H,Raz A,Hosokawa M

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Reference34 articles.

1. Akakura N, Kobayashi M, Horiuchi I, Suzuki A, Wang J, Chen J, Niizeki H, Kawamura K, Hosokawa M and Asaka M (2001) Constitutive expression of hypoxia-inducible factor-1α (HIF-1α) renders pancreatic cancer cells resistant to apoptosis induced by hypoxia and nutrient deprivation. Cancer Res 61: 6548–6554

2. Albrecht-Buehler G (1977) Phagokinetic tracks of 3T3 cells: parallels between the orientation of track segments and of cellular structures which contain actin or tubulin. Cell 11: 395–404

3. Biroccio A, Candiloro A, Mottolese M, Sapora O, Albini A, Zupi G and Del Bufalo D (2000) Bcl-2 overexpression and hypoxia synergistically act to modulate vascular endothelial growth factor expression and in vivo angiogenesis in a breast carcinoma line. FASEB J 14: 652–660

4. Blancher C and Harris AL (1998) The molecular basis of the hypoxia response pathway: tumour hypoxia as a therapy target. Cancer Metas Rev 17: 187–194

5. Brizel DM, Scully SP, Harrelson JM, Layfield LJ, Bean JM, Pronitz LR, Samulski TV, Prosnitz LR and Dewhirst MW (1996) Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma. Cancer Res 56: 941–943

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