Single-step doxorubicin-selected cancer cells overexpress the ABCG2 drug transporter through epigenetic changes

Author:

Calcagno A M,Fostel J M,To K K W,Salcido C D,Martin S E,Chewning K J,Wu C-P,Varticovski L,Bates S E,Caplen N J,Ambudkar S V

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Reference44 articles.

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2. Allen JD, Jackson SC, Schinkel AH (2002) A mutation hot spot in the Bcrp1 (Abcg2) multidrug transporter in mouse cell lines selected for doxorubicin resistance. Cancer Res 62: 2294–2299

3. Allen TM, Cheng WW, Hare JI, Laginha KM (2006) Pharmacokinetics and pharmacodynamics of lipidic nano-particles in cancer. Anti-Cancer Agents Med Chem (Formerly Curr Med Chem Anti-Cancer Agents) 6: 513–523

4. Baker EK, Johnstone RW, Zalcberg JR, El-Osta A (2005) Epigenetic changes to the MDR1 locus in response to chemotherapeutic drugs. Oncogene 24: 8061–8075

5. Barrand MA, Heppell-Parton AC, Wright KA, Rabbitts PH, Twentyman PR (1994) A 190-kilodalton protein overexpressed in non-P-glycoprotein-containing multidrug-resistant cells and its relationship to the MRP gene. J Natl Cancer Inst 86: 110–117

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