Immunotherapy with concurrent subcutaneous GM-CSF, low-dose IL-2 and IFN-α in patients with progressive metastatic renal cell carcinoma

Author:

Verra N,Jansen R,Groenewegen G,Mallo H,Kersten M J,Bex A,Vyth-Dreese F A,Sein J,van de Kasteele W,Nooijen W J,de Waal M,Horenblas S,de Gast G C

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Reference26 articles.

1. Bukowski RM (1997) Natural history and therapy of metastatic renal cell carcinoma: the role of interleukin-2. Cancer 80: 1198–1220

2. Bukowski RM (1999) Immunotherapy in renal cell carcinoma. Oncology (Huntingt) 13: 801–810

3. Bukowski RM (2000) Cytokine combinations: therapeutic use in patients with advanced renal cell carcinoma. Semin Oncol 27: 204–212

4. de Gast GC, Klumpen HJ, Vyth-Dreese FA, Kersten MJ, Verra NC, Sein J, Batchelor D, Nooijen WJ, Schornagel JH (2000) Phase I trial of combined immunotherapy with subcutaneous granulocyte macrophage colony-stimulating factor, low-dose interleukin 2, and interferon alpha in progressive metastatic melanoma and renal cell carcinoma. Clin Cancer Res 6: 1267–1272

5. Favrot MC, Combaret V, Negrier S, Philip I, Thiesse P, Freydel C, Bijmann JT, Franks CR, Mercatello A, Philip T (1990) Functional and immunophenotypic modifications induced by interleukin-2 did not predict response to therapy in patients with renal cell carcinoma. J Biol Response Mod 9: 167–177

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