DNA damage and cell cycle arrest induced by 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole (5F 203, NSC 703786) is attenuated in aryl hydrocarbon receptor deficient MCF-7 cells

Author:

Trapani V,Patel V,Leong C-O,Ciolino H P,Yeh G C,Hose C,Trepel J B,Stevens M F G,Sausville E A,Loaiza-Pérez A I

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Reference33 articles.

1. Bradshaw TD, Bibby MC, Double JA, Fichtner I, Cooper PA, Alley MC, Donohue S, Stinson SF, Tomaszewjski JE, Sausville EA, Stevens MFG (2002) Preclinical evaluation of amino acid prodrugs of novel antitumor 2-(4-amino-3-methylphenyl)benzothiazoles. Mol Cancer Ther 1: 239–246

2. Bradshaw TD, Chua M-S, Browne HL, Trapani V, Sausville EA, Stevens MFG (2000) In vitro evaluation of amino acid prodrugs of novel antitumour 2-(4-amino-3-methylphenyl)benzothiazoles. Br J Cancer 86: 1348–1354

3. Bradshaw TD, Shi D-F, Schultz RJ, Paull KD, Kelland L, Wilson A, Garner C, Fiebig H, Wrigley S, Stevens MFG (1998a) Influence of 2-(4-aminophenyl)benzothiazoles on growth of human ovarian carcinoma cells in vitro and in vivo. Br J Cancer 78: 421–429

4. Bradshaw TD, Wrigley S, Shi D-F, Schultz RJ, Paull KD, Stevens MFG (1998b) 2-(4-Aminophenyl)benzothiazoles: novel agents with selective profiles of in vitro antitumour activity. Br J Cancer 77: 745–752

5. Brantley EJ, Trapani V, Stinson SF, Stevens MFG (2001) Metabolism and subcellular binding of novel fluorinated 2-(4-amino-3-methylphenyl)benzothiazoles in human cancer cells. Proc Am Assoc Cancer Res 42: 325

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