An anti-CD30 single-chain Fv selected by phage display and fused to Pseudomonas exotoxin A (Ki-4(scFv)-ETA’) is a potent immunotoxin against a Hodgkin-derived cell line

Author:

Klimka A,Barth S,Matthey B,Roovers R C,Lemke H,Hansen H,Arends J-W,Diehl V,Hoogenboom H R,Engert A

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Reference30 articles.

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2. Barth, S., Huhn, M., Wels, W., Diehl, V. & Engert, A. (1998). Construction and in vitro evaluation of RFT5(scFv)-ETA’, a new recombinant single-chain immunotoxin with specific cytotoxicity toward CD25+ Hodgkin-derived cell lines. Int J Mol Med 1: 249–256.

3. Bradbury, A., Ruberti, F., Werge, T., Amati, V., Di Luzio, A., Gonfloni, S., Hoogenboom, H. R., Piccioli, P., Biocca, S. & Cattaneo, A. (1995). The cloning of hybridoma V regions for their ectopic expression in intracellular and intercellular immunization. In Antibody Engineering, 2nd edn. Borrebaeck COxford University Press: New York 295 .

4. Dower, W. J., Miller, J. F. & Ragsdale, C. W. (1988). High efficiency transformation of E. coli by high voltage electroporation. Nucleic Acids Res 16: 6127–6145.

5. Dürkop, H., Latza, U., Hummel, M., Eitelbach, F., Seed, B. & Stein, H. (1992). Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin’s disease. Cell 68: 421–427.

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