Uracil/ftorafur/leucovorin combined with irinotecan (TEGAFIRI) or oxaliplatin (TEGAFOX) as first-line treatment for metastatic colorectal cancer patients: results of randomised phase II study

Author:

Bajetta E, ,Di Bartolomeo M,Buzzoni R,Mariani L,Zilembo N,Ferrario E,Lo Vullo S,Aitini E,Isa L,Barone C,Jacobelli S,Recaldin E,Pinotti G,Iop A

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Reference25 articles.

1. Alonso V, Escudero P, Zorrilla M, Isla MD, herrero A, Mayordomo JI, Martines-Trufero J, Saenz A, tres A, Anton A (2001) Phase I trial of weeekly irinotecan combined with UFT as second-line treatment for advanced colorectal cancer. Eur J Cancer 37: 2385–2391

2. Bajetta E, Di Bartolomeo M, Mariani L, Cassata A, Artale S, Frustaci S, Pinotti G, Bonetti A, Carreca I, Biasco G, Bonaglia L, Marini G, Iannelli A, Cortinovis D, Ferrario E, Beretta E, Lambiase A, Buzzoni R (2004) Randomized multicenter phase II trial of two different schedules of irinotecan combined to capecitabine as first line treatment in metastatic colorectal cancer. Cancer 100: 279–287

3. Bennouna J, Perrier H, Paillot B, Priou F (2006) A phase II study of oral uracil/ftorafur (UFT) plus leucovorin combinae with oxaliplatin(TEGAFOX) as first-line treatment in patients with metastatic colorectal cancer. Br J Cancer 94: 69–73

4. Carmichael J, Popiela T, Radstone D, Falk S, Borner M, Oza A, Skovsgaard T, Munier S, Martin C (2002) Randomized comparative study of tegafur/uracil and oral leucovorin vs parenteral fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer. J Clin Oncol 20: 3617–3627

5. Colucci G, Gebbia V, Paletti GC, Giuliani F, Caruso M, Gebbia N, Carteni G, Agostara B, Pezzella G, Manzione L, Borsellino N, Misino A, Romito S, Durini E, Cordio S, Di Seri M, Lopez M, Maiello E, Montemurro S, Cramarossa A, Lorusso V, Di Bisceglie M, Chiarenza M, Valerio MR, Guida T, Leonardi V, Pisconti S, Rosati G, Carrozza F, Nettis G, Valdesi M, Filippelli G, Fortunato S, Mancarella S, Brunetti C, Gruppo Oncologico Dell'Italia Meridionale (2005) Phase III randomized trial of FOLFIRI vs FOLFOX4 in the treatment of advanced colorectal cancer: a multicenter study of the Gruppo Oncologico dell'Italia Meridionale (GOIM). J Clin Oncol 23: 4866–4875

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