From sequence to phenotype: reverse genetics in drosophila melanogaster
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics(clinical),Genetics,Molecular Biology
Link
http://www.nature.com/articles/nrg752.pdf
Reference75 articles.
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2. Adams, M. D. et al. The genome sequence of Drosophila melanogaster. Science 287, 2185–2196 (2000).
3. Lewis, E. B. & Bacher, F. Method for feeding ethyl-methane sulfonate (EMS) to Drosophila males. Drosoph. Inf. Serv. 43, 193 (1968).
4. Pastink, A., Heemskerk, E., Nivard, M., Van Vliet, C. & Vogel, E. Mutational specificity of ethyl methanesulfonate in excision-repair-proficient and -deficient strains of Drosophila melanogaster. Mol. Gen. Genet. 229, 213–218 (1991).
5. Bentley, A., MacLennan, B., Calvo, J. & Dearolf, C. Targeted recovery of mutations in Drosophila. Genetics 156, 1169–1173 (2000).This paper describes the use of DHPLC to screen for de novo mutations in a specific gene of interest in Drosophila , after EMS mutagenesis.
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