A search for synergy in the binding kinetics of Trastuzumab and Pertuzumab whole and F(ab) to Her2
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Radiology Nuclear Medicine and imaging,Oncology
Link
http://www.nature.com/articles/npjbcancer201512.pdf
Reference5 articles.
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2. Fuentes G, Scaltriti M, Baselga J, Verma CS . Synergy between trastuzumab and pertuzumab for human epidermal growth factor 2 (Her2) from colocalization: an in silico based mechanism. Breast Cancer Res 2011; 13: R54.
3. Karagiannis P, Singer J, Hunt J, Gan SKE, Rudman SM, Mechtcheriakova D et al. Characterisation of an engineered trastuzumab IgE antibody and effector cell mechanisms targeting HER2/neu-positive tumour cells. Cancer Immunol Immunother 2009; 58: 915–930.
4. Cass RM, Anderson BR . The disappearance rate of skin sensitizing antibody activity after intradermal administration. J Allergy 1968; 42: 29–35.
5. Wan T, Beavil RL, Fabiane SM, Beavil AJ, Sohi MK, Keown M et al. The crystal structure of IgE Fc reveals an asymmetrically bent conformation. Nat Immunol 2002; 3: 681–686.
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