The impact of ABCC11 polymorphisms on the risk of early-onset fluoropyrimidine toxicity-Reference-Cited by-同舟云学术

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The impact of ABCC11 polymorphisms on the risk of early-onset fluoropyrimidine toxicity

Published:2016-03-22 Issue:4 Volume:17 Page:319-324
ISSN:1470-269X
Container-title:The Pharmacogenomics Journal
language:en
Short-container-title:Pharmacogenomics J

Author:

Hamzic S,Wenger N,Froehlich T K,Joerger M,Aebi S,Largiadèr C R,Amstutz U

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology,Genetics,Molecular Medicine

Link

https://www.nature.com/articles/tpj201623.pdf

Reference32 articles.

1. Amstutz U, Froehlich TK, Largiadèr CR . Dihydropyrimidine dehydrogenase gene as a major predictor of severe 5-fluorouracil toxicity. Pharmacogenomics 2011; 12: 1321–1336.

2. Meulendijks D, Henricks LM, Sonke GS, Deenen MJ, Froehlich TK, Amstutz U et al. Clinical relevance of DPYD variants c.1679T>G, c.1236G>A/HapB3, and c.1601G>A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of individual patient data. Lancet Oncol 2015; 16: 1639–1650.

3. Rosmarin D, Palles C, Church D, Domingo E, Jones A, Johnstone E et al. Genetic markers of toxicity from capecitabine and other fluorouracil-based regimens: investigation in the QUASAR2 study, systematic review, and meta-analysis. J Clin Oncol 2014; 32: 1031–1039.

4. Lee AM, Shi Q, Pavey E, Alberts SR, Sargent DJ, Sinicrope FA et al. DPYD variants as predictors of 5-fluorouracil toxicity in adjuvant colon cancer treatment (NCCTG N0147). J Natl Cancer Inst 2014; 106doi:10.1093/jnci/dju298.

5. Longley DB, Harkin DP, Johnston PG . 5-fluorouracil: mechanisms of action and clinical strategies. Nat Rev Cancer 2003; 3: 330–338.

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