Sub-MIC levels of purpurin inhibit membrane ATPase-mediated proton efflux activity in the human fungal pathogen Candida albicans
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology
Link
http://www.nature.com/articles/ja2013140.pdf
Reference10 articles.
1. Wenzel, R. P. & Gennings, C. Bloodstream infections due to Candida species in the intensive care unit: identifying especially high-risk patients to determine prevention strategies. Clin. Infect. Dis. 41, S389–S393 (2005).
2. Morschhäuser, J. Regulation of multidrug resistance in pathogenic fungi. Fungal Genet. Biol. 47, 94–106 (2010).
3. Davis, D. A. How human pathogenic fungi sense and adapt to pH: the link to virulence. Curr. Opin. Microbiol. 12, 365–370 (2009).
4. Kaur, S. & Mishra, P. Differential increase in cytoplasmic pH at bud and germ tube formation in Candida albicans: studies of a nongerminative variant. Can. J. Microbiol. 40, 720–723 (1994).
5. Shreaz, S. et al. Influences of cinnamic aldehydes on H+ extrusion activity and ultrastructure of Candida. J. Med. Microbiol. 62, 232–240 (2013).
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