Circulating tumor DNA validity and potential uses in metastatic breast cancer-Reference-Cited by-同舟云学术

Circulating tumor DNA validity and potential uses in metastatic breast cancer

Published:2024-03-12 Issue:1 Volume:10 Page:
ISSN:2374-4677
Container-title:npj Breast Cancer
language:en
Short-container-title:npj Breast Cancer

Author:

Amato Ottavia^ORCID,Giannopoulou Nefeli,Ignatiadis Michail^ORCID

Abstract

AbstractFollowing the first characterization of circulating tumor DNA (ctDNA) in the 1990s, recent advances led to its introduction in the clinics. At present, the European Society Of Medical Oncology (ESMO) recommendations endorse ctDNA testing in routine clinical practice for tumor genotyping to direct molecularly targeted therapies in patients with metastatic cancer. In studies on metastatic breast cancer, ctDNA has been utilized for treatment tailoring, tracking mechanisms of drug resistance, and for predicting disease response before imaging. We review the available evidence regarding ctDNA applications in metastatic breast cancer.

Funder

L'Association Jules Bordet

Publisher

Springer Science and Business Media LLC

Link

https://www.nature.com/articles/s41523-024-00626-6.pdf

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