mTORC1 is a key mediator of RON-dependent breast cancer metastasis with therapeutic potential-Reference-Cited by-同舟云学术

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mTORC1 is a key mediator of RON-dependent breast cancer metastasis with therapeutic potential

Published:2018-11-09 Issue:1 Volume:4 Page:
ISSN:2374-4677
Container-title:npj Breast Cancer
language:en
Short-container-title:npj Breast Cancer

Author:

Faham Najme,Zhao Ling,Welm Alana L.

Funder

U.S. Department of Health & Human Services | NIH | National Cancer Institute

Susan G. Komen

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Radiology, Nuclear Medicine and imaging,Oncology

Link

http://www.nature.com/articles/s41523-018-0091-5.pdf

Reference61 articles.

1. Wang, M. H., Yao, H. P. & Zhou, Y. Q. Oncogenesis of RON receptor tyrosine kinase: a molecular target for malignant epithelial cancers. Acta Pharmacol. Sin. 27, 641–650 (2006).

2. Welm, A. L. et al. The macrophage-stimulating protein pathway promotes metastasis in a mouse model for breast cancer and predicts poor prognosis in humans. Proc. Natl. Acad. Sci. U.S.A. 104, 7570–7575 (2007).

3. Wang, M. H., Wang, D. & Chen, Y. Q. Oncogenic and invasive potentials of human macrophage-stimulating protein receptor, the RON receptor tyrosine kinase. Carcinogenesis 24, 1291–1300 (2003).

4. Yao, H. P., Zhou, Y. Q., Zhang, R. & Wang, M. H. MSP-RON signalling in cancer: pathogenesis and therapeutic potential. Nat. Rev. Cancer 13, 466–481 (2013).

5. Thomas, R. M. et al. The RON receptor tyrosine kinase mediates oncogenic phenotypes in pancreatic cancer cells and is increasingly expressed during pancreatic cancer progression. Cancer Res. 67, 6075–6082 (2007).

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