Dual endothelin receptor inhibition enhances T-DM1 efficacy in brain metastases from HER2-positive breast cancer-Reference-Cited by-同舟云学术

Dual endothelin receptor inhibition enhances T-DM1 efficacy in brain metastases from HER2-positive breast cancer

Published:2019-01-15 Issue:1 Volume:5 Page:
ISSN:2374-4677
Container-title:npj Breast Cancer
language:en
Short-container-title:npj Breast Cancer

Author:

Askoxylakis Vasileios,Ferraro Gino B.,Badeaux Mark,Kodack David P.,Kirst Isabelle,Shankaraiah Ram C.^ORCID,Wong Christina S. F.,Duda Dan G.,Fukumura Dai,Jain Rakesh K.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Radiology Nuclear Medicine and imaging,Oncology

Link

http://www.nature.com/articles/s41523-018-0100-8.pdf

Reference12 articles.

1. Fitzgerald, D. P. et al. Reactive glia are recruited by highly proliferative brain metastases of breast cancer and promote tumor cell colonization. Clin. Exp. Metastas-. 25, 799–810 (2008).

2. Kim, S. W. et al. Role of the endothelin axis in astrocyte- and endothelial cell-mediated chemoprotection of cancer cells. Neuro-Oncol. 16, 1585–1598 (2014).

3. Lee, H. J. et al. Treatment of experimental human breast cancer and lung cancer brain metastases in mice by macitentan, a dual antagonist of endothelin receptors, combined with paclitaxel. Neuro Oncol. 18, 486–496 (2016).

4. Askoxylakis, V. et al. Preclinical efficacy of ado-trastuzumab emtansine in the brain microenvironment. J. Natl Cancer Inst. 108, https://doi.org/10.1093/jnci/djv313 (2016).

5. Askoxylakis, V. et al. Metadata supporting data files on the relationship between dual endothelin receptor inhibition and T-DM1 efficacy in brain metastases 2 from HER2-positive breast cancer. Nature's Research Data Services. https://doi.org/10.6084/m9.figshare.7462034 (2018).

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