SphK2 confers 5-fluorouracil resistance to colorectal cancer via upregulating H3K56ac-mediated DPD expression-Reference-Cited by-同舟云学术

SphK2 confers 5-fluorouracil resistance to colorectal cancer via upregulating H3K56ac-mediated DPD expression

Published:2020-06-16 Issue:29 Volume:39 Page:5214-5227
ISSN:0950-9232
Container-title:Oncogene
language:en
Short-container-title:Oncogene

Author:

Zhang Yu-Hang^ORCID,Shi Wen-Na^ORCID,Wu Shu-Hua^ORCID,Miao Rong-Rong^ORCID,Sun Shi-Yue^ORCID,Luo Dong-Dong^ORCID,Wan Sheng-Biao^ORCID,Guo Zhi-Kun^ORCID,Wang Wen-Yu^ORCID,Yu Xin-Feng^ORCID,Cui Shu-Xiang^ORCID,Qu Xian-Jun^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Molecular Biology

Link

http://www.nature.com/articles/s41388-020-1352-y.pdf

Reference34 articles.

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3. Seymour MT, Maughan TS, Ledermann JA, Topham C, James R, Gwyther SJ, et al. Different strategies of sequential and combination chemotherapy for patients with poor prognosis advanced colorectal cancer (MRC FOCUS): a randomised controlled trial. Lancet. 2007;370:143–52.

4. Afzal S, Gusella M, Vainer B, Vogel UB, Andersen JT, Broedbaek K, et al. Combinations of polymorphisms in genes involved in the 5-Fluorouracil metabolism pathway are associated with gastrointestinal toxicity in chemotherapy-treated colorectal cancer patients. Clin Cancer Res. 2011;17:3822–9.

5. Peters GJ, Backus HH, Freemantle S, van Triest B, Codacci-Pisanelli G, van der Wilt CL, et al. Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism. Biochim Biophys Acta. 2002;1587:194–205.

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