The Wnt-pathway corepressor TLE3 interacts with the histone methyltransferase KMT1A to inhibit differentiation in Rhabdomyosarcoma
Author:
Funder
Indian Council of Medical Research
DBT India Alliance
DST | Science and Engineering Research Board
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics,Molecular Biology
Link
https://www.nature.com/articles/s41388-023-02911-3.pdf
Reference71 articles.
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2. Yu PY, Guttridge DC. Dysregulated myogenesis in rhabdomyosarcoma. Curr Top Dev Biol. 2018;126:285–97.
3. Saini M, Verma A, Mathew SJ. SPRY2 is a novel MET interactor that regulates metastatic potential and differentiation in rhabdomyosarcoma. Cell Death Dis. 2018;9:237.
4. Li S, Chen K, Zhang Y, Barnes SD, Jaichander P, Zheng Y, et al. Twist2 amplification in rhabdomyosarcoma represses myogenesis and promotes oncogenesis by redirecting MyoD DNA binding. Genes Dev. 2019;33:626–40.
5. Kendall GC, Watson S, Xu L, LaVigne CA, Murchison W, Rakheja D, et al. PAX3-FOXO1 transgenic zebrafish models identify HES3 as a mediator of rhabdomyosarcoma tumorigenesis. Elife. 2018;7:e33800.
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