Loss of DLX3 tumor suppressive function promotes progression of SCC through EGFR

Loss of DLX3 tumor suppressive function promotes progression of SCC through EGFR–ERBB2 pathway

Published:2021-05-04 Issue:21 Volume:40 Page:3680-3694
ISSN:0950-9232
Container-title:Oncogene
language:en
Short-container-title:Oncogene

Author:

Bajpai Deepti,Mehdizadeh Spencer,Uchiyama Akihiko,Inoue Yuta,Sawaya Andrew,Overmiller Andrew,Brooks Stephen R.,Hasneen Kowser,Kellett Meghan,Palazzo Elisabetta,Motegi Sei-ichiro,Yuspa Stuart H.,Cataisson Christophe,Morasso Maria I.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Molecular Biology

Link

http://www.nature.com/articles/s41388-021-01802-9.pdf

Reference44 articles.

1. Que SK, Zwald F, Schmults C. Cutaneous squamous cell carcinoma: incidence, risk factors, diagnosis, and staging. J Am Acad Dermatol. 2018;78:237–47.

2. Karia PS, Han J, Schmults CD. Cutaneous squamous cell carcinoma: estimated incidence of disease, nodal metastastasis, and deaths from disease in the United States, 2012. J Am Acad Dermatol. 2013;68:957–66.

3. Lallas A, Pyne J, Kyrgidis A, Andreani S, Argenziano G, Cavaller A, et al. The clinical and dermoscopic features of invasive cutaneous squamous cell carcinoma depend on the histopathological grade of differentiation. Br J Dermatol. 2015;172:1308–15.

4. Cillo C, Faiella A, Cantile M, Boncinelli E. Homeobox genes and cancer. Exp Cell Res. 1999;248:1–9.

5. Abate-Shen C. Deregulated homeobox gene expression in cancer: cause or consequence? Nat Rev Cancer. 2002;2:777–85.

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