JMJD6 regulates histone H2A.X phosphorylation and promotes autophagy in triple-negative breast cancer cells via a novel tyrosine kinase activity-Reference-Cited by-同舟云学术

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JMJD6 regulates histone H2A.X phosphorylation and promotes autophagy in triple-negative breast cancer cells via a novel tyrosine kinase activity

Published:2018-09-05 Issue:7 Volume:38 Page:980-997
ISSN:0950-9232
Container-title:Oncogene
language:en
Short-container-title:Oncogene

Author:

Liu Yan,Long Yue-Hong,Wang Shu-Qing,Zhang Yuan-Yue,Li Yu-Feng,Mi Jiang-Sheng,Yu Cheng-Hua,Li De-Yan,Zhang Jing-Hua,Zhang Xiao-Jun

Funder

National Natural Science Foundation of China (National Science Foundation of China)

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Molecular Biology

Link

http://www.nature.com/articles/s41388-018-0466-y.pdf

Reference46 articles.

1. Chang B, Chen Y, Zhao Y, Bruick RK. JMJD6 is a histone arginine demethylase. Science. 2007;318:444–7.

2. Webby CJ, Wolf A, Gromak N, Dreger M, Kramer H, Kessler B, et al. Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing. Science. 2009;325:90–93.

3. Wang F, He L, Huangyang P, Liang J, Si W, Yan R, et al. JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation. PLoS Biol. 2014;12:e1001819.

4. Poulard C, Rambaud J, Lavergne E, Jacquemetton J, Renoir JM, Tredan O, et al. Role of JMJD6 in breast tumourigenesis. PLoS ONE. 2015;10:e126181.

5. Aprelikova O, Chen K, El TL, Brignatz-Guittard C, Han J, Qiu T, et al. The epigenetic modifier JMJD6 is amplified in mammary tumors and cooperates with c-Myc to enhance cellular transformation, tumor progression, and metastasis. Clin Epigenetics. 2016;8:38.

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