A low amino acid environment promotes cell macropinocytosis through the YY1-FGD6 axis in Ras-mutant pancreatic ductal adenocarcinoma
Author:
Funder
National Natural Science Foundation of China
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics,Molecular Biology
Link
https://www.nature.com/articles/s41388-021-02159-9.pdf
Reference45 articles.
1. Commisso C, Davidson SM, Soydaner-Azeloglu RG, Parker SJ, Kamphorst JJ, Hackett S, et al. Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells. Nature. 2013;497:633–7.
2. Swanson JA, Yoshida S. Macropinosomes as units of signal transduction. Philos Trans R Soc Lond B Biol Sci. 2019;374:20180157.
3. Lim JP, Gleeson PA. Macropinocytosis: an endocytic pathway for internalising large gulps. Immunol Cell Biol. 2011;89:836–43.
4. Donaldson JG. Macropinosome formation, maturation and membrane recycling: lessons from clathrin-independent endosomal membrane systems. Philos Trans R Soc Lond B Biol Sci. 2019;374:20180148.
5. Palm W, Thompson CB. Nutrient acquisition strategies of mammalian cells. Nature 2017;546:234–42.
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