Repurposed pizotifen malate targeting NRF2 exhibits anti-tumor activity through inducing ferroptosis in esophageal squamous cell carcinoma-Reference-Cited by-同舟云学术

Repurposed pizotifen malate targeting NRF2 exhibits anti-tumor activity through inducing ferroptosis in esophageal squamous cell carcinoma

Published:2023-02-25 Issue:15 Volume:42 Page:1209-1223
ISSN:0950-9232
Container-title:Oncogene
language:en
Short-container-title:Oncogene

Author:

He Xinyu^ORCID,Zhou Yubing,Chen Wenjing,Zhao Xiaokun,Duan Lina,Zhou Hao,Li Mingzhu,Yu Yin,Zhao Jimin^ORCID,Guo Yaping^ORCID,Gu Huihui,Jiang Yanan^ORCID,Dong Zigang^ORCID,Liu Kangdong^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Molecular Biology

Link

https://www.nature.com/articles/s41388-023-02636-3.pdf

Reference50 articles.

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2. Yang YM, Hong P, Xu WW, He QY, Li B Advances in targeted therapy for esophageal cancer. Signal Transduct Target Ther 2020;5. https://doi.org/10.1038/S41392-020-00323-3.

3. Lignitto L, LeBoeuf SE, Homer H, Jiang S, Askenazi M, Karakousi TR, et al. Nrf2 Activation Promotes Lung Cancer Metastasis by Inhibiting the Degradation of Bach1. Cell. 2019;178:316–29.e18. https://doi.org/10.1016/J.CELL.2019.06.003.

4. Romero R, Sayin VI, Davidson SM, Bauer MR, Singh SX, Leboeuf SE, et al. Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis. Nat Med. 2017;23:1362–8. https://doi.org/10.1038/NM.4407.

5. Tsai WC, Hueng DY, Lin CR, Yang TCK, Gao HW Nrf2 Expressions Correlate with WHO Grades in Gliomas and Meningiomas. Int J Mol Sci 2016;17. https://doi.org/10.3390/IJMS17050722.

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