PAX3-FOXO1 drives miR-486-5p and represses miR-221 contributing to pathogenesis of alveolar rhabdomyosarcoma

Author:

Hanna Jason A.,Garcia Matthew R.,Lardennois Alicia,Leavey Patrick J.,Maglic Dino,Fagnan Alexandre,Go Jonathan C.,Roach Jordan,Wang Yong-Dong,Finkelstein David,Hatley Mark E.

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Molecular Biology

Reference78 articles.

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2. Parham DM, Barr FG. Alveolar rhabdomyosarcoma. In: Fletcher CDM, Bridge JA, Hogendoorn P, Mertens F(eds.) WHO classification of tumours of soft tissue and bone. 4th ed Lyon, France: IARC; 2013. p. 130–2.

3. Shapiro DN, Sublett JE, Li B, Downing JR, Naeve CW. Fusion of PAX3 to a member of the forkhead family of transcription factors in human alveolar rhabdomyosarcoma. Cancer Res. 1993;53:5108–12.

4. Galili N, Davis RJ, Fredericks WJ, Mukhopadhyay S, Rauscher FJ III, Emanuel BS, et al. Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma. Nat Genet. 1993;5:230–5.

5. Davis RJ, D’Cruz CM, Lovell MA, Biegel JA, Barr FG. Fusion of PAX7 to FKHR by the variant t(1;13)(p36;q14) translocation in alveolar rhabdomyosarcoma. Cancer Res. 1994;54:2869–72.

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