Coupled structural transitions enable highly cooperative regulation of human CTPS2 filaments
Author:
Publisher
Springer Science and Business Media LLC
Subject
Molecular Biology,Structural Biology
Link
http://www.nature.com/articles/s41594-019-0352-5.pdf
Reference60 articles.
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3. Aronow, B., Watts, T., Lassetter, J., Washtien, W. & Ullman, B. Biochemical phenotype of 5-fluorouracil-resistant murine T-lymphoblasts with genetically altered CTP synthetase activity. J. Biol. Chem. 259, 9035–9043 (1984).
4. Carman, G. M. & Zeimetz, G. M. Regulation of phospholipid biosynthesis in the yeast Saccharomyces cerevisiae. J. Biol. Chem. 271, 13293–13296 (1996).
5. Endrizzi, J. A., Kim, H., Anderson, P. M. & Baldwin, E. P. Mechanisms of product feedback regulation and drug resistance in cytidine triphosphate synthetases from the structure of a CTP-inhibited complex. Biochemistry 44, 13491–13499 (2005).
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