Ancestral-sequence reconstruction unveils the structural basis of function in mammalian FMOs
Author:
Publisher
Springer Science and Business Media LLC
Subject
Molecular Biology,Structural Biology
Link
http://www.nature.com/articles/s41594-019-0347-2.pdf
Reference86 articles.
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3. Cruciani, G. et al. Flavin monooxygenase metabolism: why medicinal chemists should matter. J. Med. Chem. 57, 6183–6196 (2014).
4. Huijbers, M. M. E., Montersino, S., Westphal, A. H., Tischler, D. & Van Berkel, W. J. H. Flavin dependent monooxygenases. Arch. Biochem. Biophys. 544, 2–17 (2014).
5. Ziegler, D. M. Flavin-containing monooxygenases: enzymes adapted for multisubstrate specificity. Trends Pharmacol. Sci. 11, 321–324 (1990).
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