The great escape — how inorganic phosphate is released from actin filaments
Author:
Publisher
Springer Science and Business Media LLC
Subject
Molecular Biology,Structural Biology
Link
https://www.nature.com/articles/s41594-023-01102-8.pdf
Reference5 articles.
1. Merino, F., Pospich, S. & Raunser, S. Towards a structural understanding of the remodeling of the actin cytoskeleton. Semin. Cell Dev. Biol. 102, 51–64 (2020). A review article that describes the fundamental functions of actin filaments in cells and how they are regulated by ABPs.
2. Oosterheert, W. et al. Structural basis of actin filament assembly and aging. Nature 611, 374–379 (2022). This paper, which motivated our Pi release study, reveals high resolution structural insights into the assembly and aging of actin filaments.
3. Carlier, M. F. & Pantaloni, D. Direct evidence for ADP–Pi–F-actin as the major intermediate in ATP–actin polymerization. Rate of dissociation of Pi from actin filaments. Biochemistry 25, 7789–7792 (1986). This pioneering study provides evidence that ADP-Pi-bound F-actin represents a distinct, metastable state of the filament.
4. Jégou, A. et al. Individual actin filaments in a microfluidic flow reveal the mechanism of ATP hydrolysis and give insight into the properties of profilin. PLoS Biol. 9, e1001161 (2011). This paper provides conclusive evidence that Pi release from F-actin is a stochastic process and shows that Pi escapes much faster from actin subunits at the barbed end than from those at the filament core.
5. Lappalainen, P., Kotila, T., Jégou, A. & Romet-Lemonne, G. Biochemical and mechanical regulation of actin dynamics. Nat. Rev. Mol. Cell Biol. 23, 836–852 (2022). A recent review article that discusses how actin filament turnover is regulated in dynamic cellular actin networks.
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3