Molecular basis for acetyl-CoA production by ATP-citrate lyase
Author:
Publisher
Springer Science and Business Media LLC
Subject
Molecular Biology,Structural Biology
Link
http://www.nature.com/articles/s41594-019-0351-6.pdf
Reference41 articles.
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2. Chypre, M., Zaidi, N. & Smans, K. ATP-citrate lyase: a mini-review. Biochem. Biophys. Res. Commun. 422, 1–4 (2012).
3. Granchi, C. ATP citrate lyase (ACLY) inhibitors: an anti-cancer strategy at the crossroads of glucose and lipid metabolism. Eur. J. Med. Chem. 157, 1276–1291 (2018).
4. Bilen, O. & Ballantyne, C. M. Bempedoic acid (ETC-1002): an investigational inhibitor of ATP citrate lyase. Curr. Atheroscler. Rep. 18, 61 (2016).
5. Burke, A. C. & Huff, M. W. ATP-citrate lyase: genetics, molecular biology and therapeutic target for dyslipidemia. Curr. Opin. Lipidol. 28, 193–200 (2017).
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