Accurate design of translational output by a neural network model of ribosome distribution
Author:
Publisher
Springer Science and Business Media LLC
Subject
Molecular Biology,Structural Biology
Link
http://www.nature.com/articles/s41594-018-0080-2.pdf
Reference46 articles.
1. Ishimura, R. et al. Ribosome stalling induced by mutation of a CNS-specific tRNA causes neurodegeneration. Science 345, 455–459 (2014).
2. Goodarzi, H. et al. Modulated expression of specific tRNAs drives gene expression and cancer progression. Cell 165, 1416–1427 (2016).
3. Kirchner, S. et al. Alteration of protein function by a silent polymorphism linked to tRNA abundance. PLoS Biol. 15, e2000779 (2017).
4. Zhao, F., Yu, C.-H. & Liu, Y. Codon usage regulates protein structure and function by affecting translation elongation speed in Drosophila cells. Nucleic Acids Res. 45, 8484–8492 (2017).
5. Shah, P., Ding, Y., Niemczyk, M., Kudla, G. & Plotkin, J. B. Rate-limiting steps in yeast protein translation. Cell 153, 1589–1601 (2013).
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