An embedded lipid in the multidrug transporter LmrP suggests a mechanism for polyspecificity-Reference-Cited by-同舟云学术

An embedded lipid in the multidrug transporter LmrP suggests a mechanism for polyspecificity

Published:2020-07-27 Issue:9 Volume:27 Page:829-835
ISSN:1545-9993
Container-title:Nature Structural & Molecular Biology
language:en
Short-container-title:Nat Struct Mol Biol

Author:

Debruycker Vincent,Hutchin Andrew^ORCID,Masureel Matthieu,Ficici Emel,Martens Chloé,Legrand Pierre^ORCID,Stein Richard A.,Mchaourab Hassane S.,Faraldo-Gómez José D.,Remaut Han^ORCID,Govaerts Cédric^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Molecular Biology,Structural Biology

Link

http://www.nature.com/articles/s41594-020-0464-y.pdf

Reference67 articles.

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3. Fromm, M. F. Importance of P-glycoprotein at blood-tissue barriers. Trends Pharmacol. Sci. 25, 423–429 (2004).

4. Aller, S. G. et al. Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding. Science 323, 1718–1722 (2009).

5. Du, D. et al. Multidrug efflux pumps: structure, function and regulation. Nat. Rev. Microbiol. 16, 523–539 (2018).

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