Allelic 'choice' governs somatic hypermutation in vivo at the immunoglobulin κ-chain locus-Reference-Cited by-同舟云学术

Allelic 'choice' governs somatic hypermutation in vivo at the immunoglobulin κ-chain locus

Published:2007-06-03 Issue:7 Volume:8 Page:715-722
ISSN:1529-2908
Container-title:Nature Immunology
language:en
Short-container-title:Nat Immunol

Author:

Fraenkel Shira,Mostoslavsky Raul,Novobrantseva Tatiana I,Pelanda Roberta,Chaudhuri Jayanta,Esposito Gloria,Jung Steffen,Alt Frederick W,Rajewsky Klaus,Cedar Howard,Bergman Yehudit

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Link

http://www.nature.com/articles/ni1476.pdf

Reference49 articles.

1. Mostoslavsky, R. et al. Asynchronous replication and allelic exclusion in the immune system. Nature 414, 221–225 (2001).

2. Goldmit, M. et al. Epigenetic ontogeny of the κ locus during B cell development. Nat. Immunol. 6, 198–203 (2005).

3. Goldmit, M., Schlissel, M., Cedar, H. & Bergman, Y. Differential accessibility at the kappa chain locus plays a role in allelic exclusion. EMBO J. 21, 5255–5261 (2002).

4. Mostoslavsky, R. κ chain monoallelic demethylation and the establishment of allelic exclusion. Genes Dev. 12, 1801–1811 (1998).

5. Mostoslavsky, R., Alt, F.W. & Rajewsky, K. The lingering enigma of the allelic exclusion mechanism. Cell 118, 539–544 (2004).

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