Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation-Reference-Cited by-同舟云学术

Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation

Published:2016-07 Issue:7612 Volume:535 Page:448-452
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Staus Dean P.,Strachan Ryan T.,Manglik Aashish,Pani Biswaranjan,Kahsai Alem W.,Kim Tae Hun,Wingler Laura M.,Ahn Seungkirl,Chatterjee Arnab,Masoudi Ali,Kruse Andrew C.,Pardon Els,Steyaert Jan,Weis William I.,Prosser R. Scott,Kobilka Brian K.,Costa Tommaso,Lefkowitz Robert J.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature18636.pdf

Reference36 articles.

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3. Kofuku, Y. et al. Efficacy of the β2-adrenergic receptor is determined by conformational equilibrium in the transmembrane region. Nature Commun. 3, 1045 (2012)

4. Nygaard, R. et al. The dynamic process of β2-adrenergic receptor activation. Cell 152, 532–542 (2013)

5. Manglik, A. et al. Structural insights into the dynamic process of β2-adrenergic receptor signaling. Cell 161, 1101–1111 (2015)

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