The phosphatase DUSP2 controls the activity of the transcription activator STAT3 and regulates TH17 differentiation-Reference-Cited by-同舟云学术

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The phosphatase DUSP2 controls the activity of the transcription activator STAT3 and regulates TH17 differentiation

Published:2015-12 Issue:12 Volume:16 Page:1263-1273
ISSN:1529-2908
Container-title:Nature Immunology
language:en
Short-container-title:Nat Immunol

Author:

Lu Dan,Liu Liang,Ji Xin,Gao Yanan,Chen Xi,Liu Yu,Liu Yang,Zhao Xuyang,Li Yan,Li Yunqiao,Jin Yan,Zhang Yu,McNutt Michael A,Yin Yuxin

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Link

http://www.nature.com/articles/ni.3278.pdf

Reference46 articles.

1. Korn, T., Bettelli, E., Oukka, M. & Kuchroo, V.K. IL-17 and Th17 cells. Annu. Rev. Immunol. 27, 485–517 (2009).

2. Yang, X.O. et al. T helper 17 lineage differentiation is programmed by orphan nuclear receptors RORα and RORγ. Immunity 28, 29–39 (2008).

3. Yang, X.O. et al. STAT3 regulates cytokine-mediated generation of inflammatory helper T cells. J. Biol. Chem. 282, 9358–9363 (2007).

4. Yang, X.P. et al. Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5. Nat. Immunol. 12, 247–254 (2011).

5. Chaudhry, A. et al. CD4+ regulatory T cells control TH17 responses in a Stat3-dependent manner. Science 326, 986–991 (2009).

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