PD-L1 predicts poor prognosis for nasopharyngeal carcinoma irrespective of PD-1 and EBV-DNA load

Author:

Zhou Yajuan,Shi Dingbo,Miao Jingjing,Wu Haijun,Chen Jiewei,Zhou Xiaoyi,Hu Desheng,Zhao Chong,Deng Wuguo,Xie Conghua

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Reference59 articles.

1. Strazzulla, A. et al. Nasopharyngeal carcinoma: review of the literature with a focus on therapeutical implications. Infez Med. 23, 224–229 (2015).

2. Sun, X. et al. Long-term outcomes of intensity-modulated radiotherapy for 868 patients with nasopharyngeal carcinoma: an analysis of survival and treatment toxicities. Radiother Oncol. 110, 398–403 (2014).

3. Li, A. C. et al. Distant metastasis risk and patterns of nasopharyngeal carcinoma in the era of IMRT: long-term results and benefits of chemotherapy. Oncotarget. 6, 24511–24521 (2015).

4. Khanna, R. et al. Molecular characterization of antigen-processing function in nasopharyngeal carcinoma (NPC): evidence for efficient presentation of Epstein-Barr virus cytotoxic T-cell epitopes by NPC cells. Cancer Res. 58, 310–314 (1998).

5. Pai, S. et al. Nasopharyngeal carcinoma-associated Epstein-Barr virus-encoded oncogene latent membrane protein 1 potentiates regulatory T-cell function. Immunol Cell Biol. 85, 370–377 (2007).

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