Characterization of genetically engineered mouse models carrying Col2a1-cre-induced deletions of Lrp5 and/or Lrp6-Reference-Cited by-同舟云学术

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Characterization of genetically engineered mouse models carrying Col2a1-cre-induced deletions of Lrp5 and/or Lrp6

Published:2016-03-01 Issue:1 Volume:4 Page:
ISSN:2095-6231
Container-title:Bone Research
language:en
Short-container-title:Bone Res

Author:

Schumacher Cassie A,Joiner Danese M,Less Kennen D,Drewry Melissa Oosterhouse,Williams Bart O

Publisher

Springer Science and Business Media LLC

Subject

Physiology,Histology,Endocrinology, Diabetes and Metabolism

Link

http://www.nature.com/articles/boneres201542.pdf

Reference58 articles.

1. Maupin KA, Droscha CJ, Williams BO . A comprehensive overview of skeletal phenotypes associated with alterations in Wnt/beta-catenin signaling in humans and mice. Bone Res 2013; 1: 27–71.

2. Joiner DM, Ke J, Zhong Z et al. LRP5 and LRP6 in development and disease. Trends Endocrinol Metab 2013; 24: 31–39.

3. Yuan X, Liu H, Huang H et al. The key role of canonical Wnt/beta-catenin signaling in cartilage chondrocytes. Curr Drug Targets 2015; 17: 475–485.

4. Shin Y, Huh YH, Kim K et al. Low-density lipoprotein receptor-related protein 5 governs Wnt-mediated osteoarthritic cartilage destruction. Arthritis Res Ther 2014; 16: R37.

5. Maruyama T, Jiang M, Hsu W . Gpr177, a novel locus for bone mineral density and osteoporosis, regulates osteogenesis and chondrogenesis in skeletal development. J Bone Miner Res 2013; 28: 1150–1159.

Cited by 20 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Wnt signaling: Essential roles in osteoblast differentiation, bone metabolism and therapeutic implications for bone and skeletal disorders;Genes & Diseases;2022-08

2. An LRP6 mutation (Arg360His) associated with low bone mineral density but not cardiovascular events in a Caucasian family;Osteoporosis International;2022-07-15

3. Wnt Pathway Extracellular Components and Their Essential Roles in Bone Homeostasis;Genes;2022-01-13

4. The Effect of Overexpression of Lrp5 on the Temporomandibular Joint;CARTILAGE;2020-10-30

5. A CRISPR-engineered swine model of COL2A1 deficiency recapitulates altered early skeletal developmental defects in humans;Bone;2020-08

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