Error-corrected next-generation sequencing to advance nonclinical genotoxicity and carcinogenicity testing-Reference-Cited by-同舟云学术

Error-corrected next-generation sequencing to advance nonclinical genotoxicity and carcinogenicity testing

Published:2023-01-16 Issue:3 Volume:22 Page:165-166
ISSN:1474-1776
Container-title:Nature Reviews Drug Discovery
language:en
Short-container-title:Nat Rev Drug Discov

Author:

Marchetti Francesco,Cardoso Renato,Chen Connie L.,Douglas George R.,Elloway Joanne,Escobar Patricia A.,Harper Jr Tod,Heflich Robert H.,Kidd Darren,Lynch Anthony M.,Myers Meagan B.,Parsons Barbara L.,Salk Jesse J.,Settivari Raja S.,Smith-Roe Stephanie L.,Witt Kristine L.,Yauk Carole,Young Robert R.,Zhang Shaofei,Minocherhomji Sheroy

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.nature.com/articles/d41573-023-00014-y.pdf

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2. Salk, J. J., Schmitt, M. W. & Loeb, L. A. Enhancing the accuracy of next-generation sequencing for detecting rare and subclonal mutations. Nat. Rev. Genet. 19, 269–285, (2018).

3. Wang, Y. et al. Genetic toxicity testing using human in vitro organotypic airway cultures: assessing DNA damage with the CometChip and mutagenesis by Duplex Sequencing. Environ. Mol. Mutagen. 62, 306–318 (2021).

4. Valentine, C. C. III et al. Direct quantification of in vivo mutagenesis and carcinogenesis using duplex sequencing. Proc. Natl Acad. Sci. USA 117, 33414–33425 (2020).

5. Fielden, M. R. et al. Modernizing human cancer risk assessment of therapeutics. Trends Pharmacol. Sci. 39, 232–247 (2018).

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