The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor-Reference-Cited by-同舟云学术

The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor

Published:2011-03-21 Issue:29 Volume:30 Page:3207-3221
ISSN:0950-9232
Container-title:Oncogene
language:en
Short-container-title:Oncogene

Author:

Renault V M,Thekkat P U,Hoang K L,White J L,Brady C A,Kenzelmann Broz D,Venturelli O S,Johnson T M,Oskoui P R,Xuan Z,Santo E E,Zhang M Q,Vogel H,Attardi L D,Brunet A

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Molecular Biology

Link

http://www.nature.com/articles/onc201135.pdf

Reference94 articles.

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2. Arum O, Johnson TE . (2007). Reduced expression of the Caenorhabditis elegans p53 ortholog cep-1 results in increased longevity. J Gerontol A Biol Sci Med Sci 62: 951–959.

3. Attardi LD, Reczek EE, Cosmas C, Demicco EG, McCurrach ME, Lowe SW et al. (2000). PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family. Genes Dev 14: 704–718.

4. Bakker WJ, Harris IS, Mak TW . (2007). FOXO3a is activated in response to hypoxic stress and inhibits HIF1-induced apoptosis via regulation of CITED2. Mol Cell 28: 941–953.

5. Bauer JH, Poon PC, Glatt-Deeley H, Abrams JM, Helfand SL . (2005). Neuronal expression of p53 dominant-negative proteins in adult Drosophila melanogaster extends life span. Curr Biol 15: 2063–2068.

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