Pdcd4 directly binds the coding region of c-myb mRNA and suppresses its translation
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics,Molecular Biology
Link
http://www.nature.com/articles/onc2011202.pdf
Reference43 articles.
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2. Asangani IA, Rasheed SA, Nikolova DA, Leupold JH, Colburn NH, Post S et al. (2008). MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene 27: 2128–2136.
3. Appl H, Klempnauer K-H . (2002). Targeted disruption of c-myb in the chicken pre B-cell line DT40. Oncogene 21: 3076–3081.
4. Bitomsky N, Böhm M, Klempnauer K-H . (2004). Transformation suppressor protein Pdcd4 interferes with JNK-mediated phosphorylation of c-Jun and recruitment of the coactivator p300 by c-Jun. Oncogene 23: 7484–7493.
5. Bitomsky N, Wethkamp N, Marikkannu R, Klempnauer K-H . (2008). siRNA-mediated knock-down of Pdcd4 expression causes up-regulation of p21(Waf1/Cip1) expression. Oncogene 27: 4820–4829.
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