Role of connexin43 and ATP in long-range bystander radiation damage and oncogenesis in vivo

Author:

Mancuso M,Pasquali E,Leonardi S,Rebessi S,Tanori M,Giardullo P,Borra F,Pazzaglia S,Naus C C,Di Majo V,Saran A

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Molecular Biology

Reference29 articles.

1. Amino M, Yoshioka K, Tanabe T, Tanaka E, Mori H, Furusawa Y et al. (2006). Heavy ion radiation up-regulates Cx43 and ameliorates arrhythmogenic substrates in hearts after myocardial infarction. Cardiovasc Res 72: 412–421.

2. Azzam EI, de Toledo SM, Gooding T, Little JB . (1998). Intercellular communication is involved in the bystander regulation of gene expression in human cells exposed to very low fluences of alpha particles. Radiat Res 150: 497–504.

3. Azzam EI, de Toledo SM, Little JB . (2003). Expression of connexin43 is highly sensitive to ionizing radiation and other environmental stresses. Cancer Res 63: 7128–7135.

4. Azzam EI, de Toledo SM, Spitz DR, Little JB . (2002). Oxidative metabolism modulates signal transduction and micronucleus formation in bystander cells from alpha-particle-irradiated normal human fibroblast cultures. Cancer Res 62: 5436–5442.

5. BEIR VII (2006). Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation, National Research Council. Health risks from exposure to low levels of ionizing radiation: BEIR VII phase 2. National Academies Press: Washington, DC.

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