Either Kras activation or Pten loss similarly enhance the dominant-stable CTNNB1-induced genetic program to promote granulosa cell tumor development in the ovary and testis
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics,Molecular Biology
Link
http://www.nature.com/articles/onc2011341.pdf
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3. Boerboom D, White LD, Dalle S, Courty J, Richards JS . (2006). Dominant-stable-cateni b-catenin expression causes cell fate alterations and Wnt signaling antagonist expression in a murine granulosa cell model. Cancer Res 66: 1964–1973.
4. Boyer A, Goff AK, Boerboo D . (2009a). WNT signaling in ovarian follicle biology and tumorigenesis. Trends in Endocrinol Metab 21: 25–32.
5. Boyer A, Hermo L, paquet M, Robaire B, Boerboom D . (2008). Seminiferous tubule degeneration and infertility in mice with sustained activation of WNT/CTNNB1 signaling in Sertoli cells. Biol Reprod 79: 2062–2072.
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