Novel inhibitors of Mycobacterium tuberculosis GuaB2 identified by a target based high-throughput phenotypic screen-Reference-Cited by-同舟云学术

Novel inhibitors of Mycobacterium tuberculosis GuaB2 identified by a target based high-throughput phenotypic screen

Published:2016-12 Issue:1 Volume:6 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Cox Jonathan A. G.,Mugumbate Grace,Del Peral Laura Vela-Glez,Jankute Monika,Abrahams Katherine A.,Jervis Peter,Jackenkroll Stefan,Perez Arancha,Alemparte Carlos,Esquivias Jorge,Lelièvre Joël,Ramon Fernando,Barros David,Ballell Lluis,Besra Gurdyal S.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/srep38986.pdf

Reference26 articles.

1. World Health Organization (WHO). Global Tuberculosis Report (2015).

2. Velayati, A. A. et al. Emergence of new forms of totally drug-resistant tuberculosis bacilli: super extensively drug-resistant tuberculosis or totally drug-resistant strains in Iran. Chest. 136, 420–425 (2009).

3. Udwadia, Z. F., Amale, R. A., Ajbani, K. K. & Rodrigues C. Totally drug-resistant tuberculosis in India. Clin. Infect. Dis. 54, 579–581 (2012).

4. Zumla, A., Nahid, P. & Cole, S. T. Advances in the development of new tuberculosis drugs and treatment regimens. Nat. Rev. Drug Discov. 12, 388–404 (2013).

5. Zwarenstein, M., Schoeman, J. H., Vundule, C., Lombard, C. J. & Tatley, M. Randomised controlled trial of self-supervised and directly observed therapy for tuberculosis. Lancet. 352, 1340–1343 (1998).

Cited by 28 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Differential effects of inosine monophosphate dehydrogenase (IMPDH/GuaB) inhibition in Acinetobacter baumannii and Escherichia coli;Journal of Bacteriology;2024-09-05

2. Discovery of GuaB inhibitors with efficacy against Acinetobacter baumannii infection;mBio;2024-08-29

3. Deciphering the allosteric regulation of mycobacterial inosine-5′-monophosphate dehydrogenase;Nature Communications;2024-08-06

4. Discovery of isoquinoline sulfonamides as allosteric gyrase inhibitors with activity against fluoroquinolone-resistant bacteria;Nature Chemistry;2024-06-19

5. New synergistic benzoquinone scaffolds as inhibitors of mycobacterial cytochrome bc1 complex to treat multi-drug resistant tuberculosis;European Journal of Medicinal Chemistry;2024-06