Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes

Author:

Romanov Serguei R.,Kozakiewicz B. Krystyna,Holst Charles R.,Stampfer Martha R.,Haupt Larisa M.,Tlsty Thea D.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Reference28 articles.

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3. Hammond, S. L., Ham, R. G. & Stampfer, M. R. Serum-free growth of human mammary epithelial cells: rapid clonal growth in defined medium and extended passage with pituitary extract. Proc. Natl Acad. Sci. USA 81, 5435–5439 (1984).

4. Foster, S. A. & Galloway, D. A. Human papillomavirus type 16 E7 alleviates a proliferation block in early passage human mammary epithelial cells. Oncogene 12, 1773–1779 (1996).

5. Huschtscha, L. I. et al. Loss of p16INK4 expression by methylation is associated with lifespan extension of human mammary epithelial cells. Cancer Res. 58, 3508–3512 (1998).

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