Pseudomonas aeruginosa adaptation and evolution in patients with cystic fibrosis
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Immunology and Microbiology,Microbiology,Infectious Diseases
Link
http://www.nature.com/articles/s41579-020-00477-5.pdf
Reference122 articles.
1. Ratjen, F. & Döring, G. Cystic fibrosis. Lancet 361, 681–689 (2003).
2. Marvig, R. L., Sommer, L. M., Molin, S. & Johansen, H. K. Convergent evolution and adaptation of Pseudomonas aeruginosa within patients with cystic fibrosis. Nat. Genet. 47, 57–64 (2015). This paper presents the comprehensive genomic analysis of a collection of longitudinal P. aeruginosa isolates from several patients with early-stage infections, used to define a set of pathoadaptive genes.
3. Marvig, R. L., Johansen, H. K., Molin, S. & Jelsbak, L. Genome analysis of a transmissible lineage of Pseudomonas aeruginosa reveals pathoadaptive mutations and distinct evolutionary paths of hypermutators. PLoS Genet. 9, e1003741 (2013).
4. Williams, D. et al. Divergent, coexisting Pseudomonas aeruginosa lineages in chronic cystic fibrosis lung infections. Am. J. Respir. Crit. Care Med. 191, 775–785 (2015).
5. Cramer, N. et al. Microevolution of the major common Pseudomonas aeruginosa clones C and PA14 in cystic fibrosis lungs. Environ. Microbiol. 13, 1690–1704 (2011).
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