Sewage surveillance of antibiotic resistance holds both opportunities and challenges

Author:

Larsson D. G. JoakimORCID,Flach Carl-FredrikORCID,Laxminarayan Ramanan

Publisher

Springer Science and Business Media LLC

Subject

General Immunology and Microbiology,Microbiology,Infectious Diseases

Reference10 articles.

1. Huijbers, P. M. C., Flach, C.-F. & Larsson, D. G. J. A conceptual framework for the environmental surveillance of antibiotics and antibiotic resistance. Environ. Int. 130, 104880 (2019).

2. Aarestrup, F. M. & Woolhouse, M. E. J. Using sewage for surveillance of antimicrobial resistance. Science 367, 630–632 (2020).

3. European Commission. Proposal for a revised Urban Wastewater Treatment Directive. European Commission https://environment.ec.europa.eu/publications/proposal-revised-urban-wastewater-treatment-directive_en (2022).

4. US Centres for Disease Control and Prevention. COVID-19 impacts on environment (e.g., water, soil) and sanitation: addressing antimicrobials and antimicrobial resistant threats in the environment. US Centres for Disease Control and Prevention https://www.cdc.gov/drugresistance/pdf/covid19/COVID19-Impacts-AR-Environment-Sanitation-508.pdf (2021).

5. Flach, C.-F., Hutinel, M., Razavi, M., Åhrén, C. & Larsson, D. G. J. Monitoring of hospital sewage shows both promise and limitations as an early-warning system for carbapenemase-producing Enterobacterales in a low-prevalence setting. Water Res. 200, 117261 (2021).

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