A community computational challenge to predict the activity of pairs of compounds-Reference-Cited by-同舟云学术

A community computational challenge to predict the activity of pairs of compounds

Published:2014-11-17 Issue:12 Volume:32 Page:1213-1222
ISSN:1087-0156
Container-title:Nature Biotechnology
language:en
Short-container-title:Nat Biotechnol

Author:

Bansal Mukesh^ORCID, ,Yang Jichen,Karan Charles,Menden Michael P,Costello James C,Tang Hao,Xiao Guanghua,Li Yajuan,Allen Jeffrey,Zhong Rui,Chen Beibei,Kim Minsoo,Wang Tao^ORCID,Heiser Laura M,Realubit Ronald,Mattioli Michela^ORCID,Alvarez Mariano J,Shen Yao,Gallahan Daniel,Singer Dinah,Saez-Rodriguez Julio^ORCID,Xie Yang,Stolovitzky Gustavo,Califano Andrea

Publisher

Springer Science and Business Media LLC

Subject

Biomedical Engineering,Molecular Medicine,Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Link

http://www.nature.com/articles/nbt.3052.pdf

Reference49 articles.

1. Rawlinson, R. & Massey, A.J. Gamma H2AX and Chk1 phosphorylation as predictive pharmacodynamic biomarkers of Chk1 inhibitor-chemotherapy combination treatments. BMC Cancer 14, 483 (2014).

2. Ibrahim, Y.H. et al. PI3K inhibition impairs BRCA1/2 expression and sensitizes BRCA-proficient triple-negative breast cancer to PARP inhibition. Cancer Discov. 2, 1036–1047 (2012).

3. Yonesaka, K. et al. Activation of ERBB2 signaling causes resistance to the EGFR-directed therapeutic antibody cetuximab. Sci. Transl. Med. 3, 99ra86 (2011).

4. Al-Lazikani, B., Banerji, U. & Workman, P. Combinatorial drug therapy for cancer in the post-genomic era. Nat. Biotechnol. 30, 679–692 (2012).

5. Keith, C.T., Borisy, A.A. & Stockwell, B.R. Multicomponent therapeutics for networked systems. Nat. Rev. Drug Discov. 4, 71–78 (2005).

Cited by 262 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Polypharmacy side effect prediction based on semi-implicit graph variational auto-encoder;Journal of Bioinformatics and Computational Biology;2024-09-12

2. CKG-IMC: An inductive matrix completion method enhanced by CKG and GNN for Alzheimer’s disease compound-protein interactions prediction;Computers in Biology and Medicine;2024-07

3. Big data-driven water research towards metaverse;Water Science and Engineering;2024-06

4. DRGATAN: Directed relation graph attention aware network for asymmetric drug-drug interaction prediction;iScience;2024-06

5. A synthetic lethal dependency on casein kinase 2 in response to replication-perturbing therapeutics in RB1-deficient cancer cells;Science Advances;2024-05-24