Pharmacological targeting of the thrombomodulin–activated protein C pathway mitigates radiation toxicity-Reference-Cited by-同舟云学术

Pharmacological targeting of the thrombomodulin–activated protein C pathway mitigates radiation toxicity

Published:2012-06-24 Issue:7 Volume:18 Page:1123-1129
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Geiger Hartmut,Pawar Snehalata A,Kerschen Edward J,Nattamai Kalpana J,Hernandez Irene,Liang Hai Po H,Fernández Jose Á,Cancelas Jose A,Ryan Marnie A,Kustikova Olga,Schambach Axel,Fu Qiang,Wang Junru,Fink Louis M,Petersen Karl-Uwe,Zhou Daohong,Griffin John H,Baum Christopher,Weiler Hartmut,Hauer-Jensen Martin

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm.2813.pdf

Reference53 articles.

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2. Kirsch, D.G. et al. p53 controls radiation-induced gastrointestinal syndrome in mice independent of apoptosis. Science 327, 593–596 (2010).

3. Schuller, B.W. et al. Selective irradiation of the vascular endothelium has no effect on the survival of murine intestinal crypt stem cells. Proc. Natl. Acad. Sci. USA 103, 3787–3792 (2006).

4. Rotolo, J.A. et al. Regulation of ceramide synthase-mediated crypt epithelium apoptosis by DNA damage repair enzymes. Cancer Res. 70, 957–967 (2010).

5. Paris, F. et al. Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice. Science 293, 293–297 (2001).

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