Reply to Rifampicin: a glucocorticoid receptor ligand?

Author:

Calleja C.,Pascussi J.M.,Mani J.C.,Maurel P.,Vilarem M.J.

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference6 articles.

1. Calleja, C., Pascussi, J. M., Mani, J.C., Maurel, P. & Vilarem, M.J. The antibiotic rifampicin is a nonsteroidal ligand and activator of the human glucocorticoid receptor. Nature Med. 4, 92–96 ( 1998).

2. Blanchard, J.S. The ying and yang of rifampicin. Nature Med. 4, 14–15 (1998).

3. Nakai, Y. et al. Molecular mechanisms of clucocorticoid inhibition of human proopiomelanocortin gene transcription. J. Steroid Biochem. Mol. Biol. 40, 301–306 (1991).

4. Barwick, J.L. et al. Trans-species gene transfer for analysis of clucocorticoid-inducible transcriptional activitation of transiently expresed human CYP3A4 and rabbit CYP3A6 in primary ultures of adult rat and rabbit hepatocytes. Mol. Pharmacol. 50, 10– 16 (1996).

5. Pichard, L. et al. Cyclosporin a druf interactions. Screening for inducers and inhibitors of cytochrome P450 (cyclosporin A oxidase) in primary cultures of human hepatocyes and in liver microsomes. Drug Met. Diaposition . 18, 595–606 ( 1990).

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